This is just... breathtakingly beautiful
While there is not much context, it looks as if this is something that happened after Hijiri got found out about protecting Youkai... and the group is then being persecuted by human...
...damn it, dust in my eyes

Artist commentary:

誰に理解されずとも

理想に殉じる　　　　　　　　　　　　■聖を殺すとしたら、それはきっと聖自身の思想や理想なのではないかと。きっと最後はまた裏切られる。　　けど、今度こそ星ちゃんは自分の立場とか全てかなぐり捨てて最期まで聖を守るのだろうなと。　　■…この絵の星ちゃんは多分もう長くないけれど最期まで聖の傍を離れないよ

WestTxTapper said:

Artist commentary:

誰に理解されずとも

理想に殉じる　　　　　　　　　　　　■聖を殺すとしたら、それはきっと聖自身の思想や理想なのではないかと。きっと最後はまた裏切られる。　　けど、今度こそ星ちゃんは自分の立場とか全てかなぐり捨てて最期まで聖を守るのだろうなと。　　■…この絵の星ちゃんは多分もう長くないけれど最期まで聖の傍を離れないよ

Well... crud, there is actually a context
Allright, lemme try some third rate moonspeaks:

Though who could not be understood

To sacrifice for the ideal　　　　　　　　　　　　■If Hijiri was to be killed, this would surely due to Hijiri’s own ideology and dream. Surely to be betrayed again in the end. But this time around, Shou-Chan, in a position such as herself, would seems to abandon all to protect Hijiri until the end.　　■…This is an image of Shou-chan who is lasting perhaps not for much longer, but she will not leave Hijiri’s side even until the end

(Quite shoddy translation... but oh well, it does the job)
So... this is an image of Hijiri grasping her belief even until dead, whereas Shou is by her side and defending her with her life till' the last breath
...I shall dry my previous tears and shed some new one
(Also, adding to "Soul-Crushingly Depressing" pool since the context fits)

Good shot, Lumine

WestTxTapper said:

誰に理解されずとも

理想に殉じる　　　　　　　　　　　　■聖を殺すとしたら、それはきっと聖自身の思想や理想なのではないかと。きっと最後はまた裏切られる。　　けど、今度こそ星ちゃんは自分の立場とか全てかなぐり捨てて最期まで聖を守るのだろうなと。　　■…この絵の星ちゃんは多分もう長くないけれど最期まで聖の傍を離れないよ

Those who are never understood

Sacrificing oneself for one's ideals

■If Hijiri was to be killed, it would be surely be because of Hijiri's own ideals and aspirations. She is inevitably betrayed again by these ideals.　However, this time, Shou-chan, in a position such as herself, throws everything she has, intending to protect Hijiri to the end. 　　■...This image's Shou-chan may not last much longer, but will not leave Hijiri’s side until the very end.