There's nothing worse for a villain than to be completely ignored when giving your introduction.
Ultimate Despair is no match for Ultimate Apathy.
Did you really think it would end there?Despair.Hah! How pathetic, Naegi!So despair!This is true despair.I am Junko Enoshima, the Super Duper High School Despair.I was ignored...
He ignored me.Oh, it opened.The truth is that all of those that you killed were your classmates who you spent two years with.Despair in the face of this apocalyptic world!